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Wednesday, June 13, 2007

Anxiety Disorders in Adults: A Clinical Guide



By Vladan Starcevic

  • Publisher:   Oxford University Press, USA
  • Number Of Pages:   440
  • Publication Date:   2004-09-30
  • Sales Rank:   1232284
  • ISBN / ASIN:   0195156064
  • EAN:   9780195156065
  • Binding:   Hardcover
  • Manufacturer:   Oxford University Press, USA
  • Studio:   Oxford University Press, USA
  • Average Rating:  
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Book Description:

Each of the adult anxiety disorders (panic disorder, generalized anxiety disorder, social anxiety disorder, specific phobias, obsessive-compulsive disorder and posttraumatic stress disorder) is presented in a separate chapter of this volume. As the rich description of each disorder is a prerequisite for their recognition, understanding and diagnosis, the book focuses on clinical features, psychopathology and the corresponding conceptual issues. There is also an emphasis of etiological factors, pathogenetic processes, and pharmacological and psychological treatments of each anxiety disorder, as adequate treatment depends crucially on the clinician's understanding of the origins of these conditions and the processes involved in their occurrence. The volume is guided by a practical need to present the anxiety disorders as they occur and as they are treated in the "real world." As such, this work is intended to be a state-of-the-art reference for clinical practice, aiming to balance and integrate what is currently known about anxiety disorders and their treatment. It contains descriptions of the relevant diagnostic and therapeutic procedures, practical tips, and treatment recommendations for the commonly encountered clinical situations. The book is most useful to psychiatrists, primary care physicians, clinical psychologists, other mental health workers, and physicians in training. It is also of interest to a general audience.

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Anxiety Disorders in Adults: An Evidence-Based Approach to Psychological Treatment



By Peter D. McLean,&nbspSheila R. Woody, 

  • Publisher:   Oxford University Press, USA
  • Number Of Pages:   369
  • Publication Date:   2001-01-15
  • Sales Rank:   510912
  • ISBN / ASIN:   0195116259
  • EAN:   9780195116250
  • Binding:   Hardcover
  • Manufacturer:   Oxford University Press, USA
  • Studio:   Oxford University Press, USA
  • Average Rating:  
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Book Description:

This is the second book in Oxford's Guidebooks in Clinical Psychology series. This book provides practical guidelines on the treatment of anxiety disorders (the second most frequent clinical diagnosis), linking guidelines to empirical evidence. The authors review the several classifications of anxiety disorders using the latest DSM-IV categories, covering specific phobias, social phobia, panic disorder and agoraphobia, obsessive-compulsive disorder, and post-traumatic stress disorder, among others. The chapters assess the efficacy of various treatments, and the authors conclude with a discussion of how treatment standards can be implemented in clinical training and practice.

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Aphasia and Its Therapy (Medicine)



By Anna Basso

  • Publisher:   Oxford University Press, USA
  • Number Of Pages:   336
  • Publication Date:   2003-01-08
  • Sales Rank:   842590
  • ISBN / ASIN:   0195135873
  • EAN:   9780195135879
  • Binding:   Hardcover
  • Manufacturer:   Oxford University Press, USA
  • Studio:   Oxford University Press, USA
  • Average Rating:  
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Book Description:

This is the first single-authored book to attempt to bridge the gap between aphasia research and the rehabilitation of patients with this language disorder. Studies of the deficits underlying aphasia and the practice of aphasia rehabilitation have often diverged, and the relationship between theory and practice in aphasiology is loose. The goal of this book is to help close this gap by making explicit the relationship between what is to be rehabilitated and how to rehabilitate it.L Early chapters cover the history of aphasia and its therapy from Broca's discoveries to the 1970's, and provide a description of the classic aphasia syndromes. The middle section describes the contribution of cognition neuropsychology and the treatment models it has inspired. It includes discussion of the relationship between the treatment approach and the functional model upon which it is based. The final chapters deal with aphasia therapy. After providing a sketch of a working theory of aphasia, Basso describes intervention procedures for disorders resulting from damage at the lexical and sentence levels as well as a more general conversation-based intervention for severe aphasics.L Anna Basso has run an aphasia rehabilitation unit for more than thirty years. In this book she draws on her considerable experience to provide researchers, clinicians, and their students and trainees with comprehensive coverage of the evolution and state of the art of aphasia research and therapy.


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Manual of Endoscopic Sinus Surgery And Its Extended Applications



By Daniel, M.D. Simmen,&nbspNick Jones, 

  • Publisher:   Thieme Medical Publishers
  • Number Of Pages:   300
  • Publication Date:   2005-05
  • Sales Rank:   358838
  • ISBN / ASIN:   1588901424
  • EAN:   9781588901422
  • Binding:   Hardcover
  • Manufacturer:   Thieme Medical Publishers
  • Studio:   Thieme Medical Publishers
  • Average Rating:  
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Asthma Epidemiology: Principles and Methods



By Neil Pearce,&nbspRichard Beasley,&nbspCarl Burgess,&nbspJulian Crane, 

  • Publisher:   Oxford University Press, USA
  • Number Of Pages:   266
  • Publication Date:   1998-01-15
  • Sales Rank:   1962389
  • ISBN / ASIN:   0195080165
  • EAN:   9780195080162
  • Binding:   Hardcover
  • Manufacturer:   Oxford University Press, USA
  • Studio:   Oxford University Press, USA
  • Average Rating:  
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Book Description:

Asthma prevalence is increasing worldwide, and there is growing concern about the burden of asthma both for patients and for the health services. There have also been major changes in the management of asthma death in some western countries in the 1960's and again in the 1970's. Asthma epidemiology has a major role to play in investigating the causes of these global changes, and in developing preventive interventions. This is the first text on the principles and methods of asthma epidemiology. It describes the types of asthma epidemiology studies, and discusses the strengths and limitations of the various methods of measuring asthma prevalence and asthma morbidity and the major risk factors for asthma, methods of studying the causes of asthma deaths. The book will therefore be of interest not only to epidemiologists, but also to the very large number of respiratory physicians, allergist, and pediatricians who are becoming involved in asthma epidemiology.

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Tuesday, June 12, 2007

Emergency Care for Children: Growing Pains (Future of Emergency Care)



By Institute of Medicine (U. S.)

  • Publisher:   National Academy Press
  • Number Of Pages:   338
  • Publication Date:   2007-05-30
  • Sales Rank:   2546377
  • ISBN / ASIN:   0309101719
  • EAN:   9780309101714
  • Binding:   Hardcover
  • Manufacturer:   National Academy Press
  • Studio:   National Academy Press
  • Average Rating:  
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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (Dietary Reference Series)



By Institute of Medicine

  • Publisher:   National Academy Press
  • Number Of Pages:   564
  • Publication Date:   2000-05
  • Sales Rank:   1977067
  • ISBN / ASIN:   0309064112
  • EAN:   9780309064118
  • Binding:   Hardcover
  • Manufacturer:   National Academy Press
  • Studio:   National Academy Press
  • Average Rating:   4
  • Total Reviews:   1

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Performance Measurement: Accelerating Improvement (Pathways to Quality Health Care)



By Institute Of Medicine

  • Publisher:   National Academy Press
  • Number Of Pages:   357
  • Publication Date:   2006-07
  • Sales Rank:   644276
  • ISBN / ASIN:   0309100070
  • EAN:   9780309100076
  • Binding:   Hardcover
  • Manufacturer:   National Academy Press
  • Studio:   National Academy Press
  • Average Rating:  
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ABOUT ANAESTHESIA AND INTENSIVE CARE MEDICINE journal


 []  

ABOUT ANAESTHESIA AND INTENSIVE CARE MEDICINE


Anaesthetists and intensivists in training will find Anaesthesia and Intensive Care Medicine an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle.

Those experienced in the field, or with training responsibilities, will find the journal provides the right level of information for updating and refreshing their knowledge, and much material suitable for use as teaching aids.

Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.

 

 

on CD-ROM presents a complete 3-year series of the journal in a fully-networkable electronic format – covering the equivalent of 36 monthly issues of the journal.

With a powerful searching facility, the CD-ROM is the ideal complement to the journal edition.

Anaesthesia and intensive care medicine

 

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CLINICAL CASEs from NEW ENGLAND JOURNAL OF MEDICINE FROM 2004 TO 2007


CLINICAL CASEs from  NEW ENGLAND JOURNAL OF MEDICINE FROM 2004 TO 2007

 

INTERSTING CLINICAL CASES WITH COMPLETE ANALYSIS OF THE CLINICAL,LABORATORY AND RADIOGRAPHIC FINDINGs.


LEARN HOW TO APPROACH THE PATIENT AND HOW TO SOLVE CLINICAL MYSTRIEs


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Exploring Complementary and Alternative Medicine (The Richard and Hinda Rosenthal Lectures, 2001)



By Institute of Medicine

  • Publisher:   National Academy Press
  • Number Of Pages:   44
  • Publication Date:   2003-02
  • Sales Rank:   4716681
  • ISBN / ASIN:   0309085039
  • EAN:   9780309085038
  • Binding:   Paperback
  • Manufacturer:   National Academy Press
  • Studio:   National Academy Press
  • Average Rating:  
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Marijuana and Medicine: Assessing the Science Base



By

  • Publisher:   National Academy Press
  • Number Of Pages:   267
  • Publication Date:   1999-07-15
  • Sales Rank:   1181466
  • ISBN / ASIN:   0309071550
  • EAN:   9780309071550
  • Binding:   Hardcover
  • Manufacturer:   National Academy Press
  • Studio:   National Academy Press
  • Average Rating:   5
  • Total Reviews:   4


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Clinical Surgery: with STUDENT CONSULT Access



By Michael M. Henry,&nbspJeremy N. Thompson, 

  • Publisher:   Saunders Ltd.
  • Number Of Pages:   824
  • Publication Date:   2004-12-20
  • Sales Rank:   837072
  • ISBN / ASIN:   0702027197
  • EAN:   9780702027192
  • Binding:   Paperback
  • Manufacturer:   Saunders Ltd.
  • Studio:   Saunders Ltd.
  • Average Rating:   4
  • Total Reviews:   2



Book Description:

First Prize (Surgery category), BMA Awards 2005. A comprehensive and attractively presented 4-colour textbook of surgery aimed primarily at medical students but also of use to junior doctors and surgical technicians. The book has two key features: firstly, it provides students with coverage of every aspect of surgery; secondly, it has been designed and written to be the surgical companion to Kumar & Clarks Clinical Medicine. This new edition will also offer an online version to all purchasers of the book the first surgical textbook in the UK to make an electronic version available.

The smart way to study!
Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.


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Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)



By

  • Publisher:   Humana Press
  • Number Of Pages:   292
  • Publication Date:   2004-12-03
  • Sales Rank:   2336194
  • ISBN / ASIN:   1588292002
  • EAN:   9781588292001
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.

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Bone Metastasis (Cancer Drug Discovery and Development)

 


By
  • Publisher:   Humana Press
  • Number Of Pages:   360
  • Publication Date:   2005-01-20
  • Sales Rank:   2624862
  • ISBN / ASIN:   158829403X
  • EAN:   9781588294036
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

A state-of-the-art review of the molecular underpinnings of bone-seeking cancers, current treatment approaches for them, and future therapeutic strategies. The authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. They also discuss the various strategies that appear to have promise and are currently deployed in treatment or are at the experimental stage.
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Ecografia Vaginal



By Carlos E. Bonilla

  • Publisher:   Editorial Medica Panamericana
  • Number Of Pages:  
  • Publication Date:   2001-10
  • Sales Rank:  
  • ISBN / ASIN:   8479035668
  • EAN:   9788479035662
  • Binding:   Paperback
  • Manufacturer:   Editorial Medica Panamericana
  • Studio:   Editorial Medica Panamericana
  • Average Rating:  
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Cardiovascular Research: New Technologies, Methods, and Applications



By

  • Publisher:   Springer
  • Number Of Pages:   239
  • Publication Date:   2005-11-16
  • Sales Rank:  
  • ISBN / ASIN:   0387233288
  • EAN:   9780387233284
  • Binding:   Hardcover
  • Manufacturer:   Springer
  • Studio:   Springer
  • Average Rating:  
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Book Description:

The last decade, technical improvements will have changed the inventory of many research laboratories. New techniques and discoveries continuously give rise to observations that consequently result in the definition of new research objectives. In the past, research departments used to be clearly demarcated. Nowadays, technology that is shared by all lines of research stimulates convergence of research interests. This also applies to cardiovascular research. Vascular occlusive disease is now core business for researchers employed by cardiology, vascular surgery, vascular medicine, radiology, cell biology, chemistry, physiology and many more departments. Knowledge on actual research developments are shared by researchers with different skills. It is sometimes difficult to acquire expertise when a researcher feels his experimental work could be improved by introducing a new research technique. In this book the investigator will find an overview of recent developments that are relevant for research in general but cardiovascular research in particular. Genomics, proteomics, micro-array, RNAi, stem cells and progenitor cells: just some phrases that became increasingly prevalent in literature the last couple of years and that are recognized by many, but fully understood by few. In this book experts in their research fields will share the most appreciated new developments and techniques in cardiovascular research. We hope that this book will help the reader, who is working in cardiovascular research, to understand and critically appreciate current research and that it will help improve the quality of the experimental work.

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Shapeshifter - DNA Activation LevelOne (4cds)

[]

Shapeshifter - DNA Activation LevelOne (4cds)
NEW-AGE | MP3 | 320kbits / 44.1kHz | 431.2Mb + 5%



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This 4 CD set is accompanied by Companion Guide. Each CD contains multi-dimensional, shapeshifting, organic soundscapes channeled with clear and impeccable intent from a deep connection with the Creative Muse. This cybershamanic ambient music is a transcendent and profoundly powerful tool for awakening and activating the full 12 strand DNA codex - our bridge between the multiple dimensions of matter and the Divine. The Companion Guide provides insightful transmissions about the vast potential of this transformational music - the next step in sound healing. From the deepest space within, waveforms of a higher implicate order resonate the Light Body and the DNA matrix, which contain the blueprint for manifesting the multidimensional wonder and magic of all that you are and can truly become.

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Auditory Cortex: Synthesis of Human and Animal Research



By

  • Publisher:   Lawrence Erlbaum Associates
  • Number Of Pages:   512
  • Publication Date:   2005-03
  • Sales Rank:   1598450
  • ISBN / ASIN:   0805849386
  • EAN:   9780805849387
  • Binding:   Hardcover
  • Manufacturer:   Lawrence Erlbaum Associates
  • Studio:   Lawrence Erlbaum Associates
  • Average Rating:  
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Book Description:

Understanding human hearing is not only a scientific challenge but also a problem of growing social and political importance, given the steadily increasing numbers of people with hearing deficits or even deafness. This book is about the highest level of

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Interactive Physiology 9-system Suite - Human Anatomy and Physiology



By Benjamin Cummings,&nbspKatja Hoehn, 

  • Publisher:   Prentice Hall College Div
  • Number Of Pages:  
  • Publication Date:   2006-05-30
  • Sales Rank:  
  • ISBN / ASIN:   0805300759
  • EAN:   9780805300758
  • Binding:   Hardcover
  • Manufacturer:   Prentice Hall College Div
  • Studio:   Prentice Hall College Div
  • Average Rating:  
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Monday, June 11, 2007

Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)



By

  • Publisher:   Humana Press
  • Number Of Pages:   384
  • Publication Date:   2004-12-03
  • Sales Rank:   2146925
  • ISBN / ASIN:   1588291723
  • EAN:   9781588291721
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.


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Platelets and Megakaryocytes: Volume 1: Functional Assays (Methods in Molecular Biology)



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  • Publisher:   Humana Press
  • Number Of Pages:   408
  • Publication Date:   2004-07-01
  • Sales Rank:   831344
  • ISBN / ASIN:   1588291014
  • EAN:   9781588291011
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:


For both volumes:

A comprehensive collection of cutting-edge methods for the molecular and cellular analysis of platelets and megakaryocytes. Volume 1 details basic and advanced techniques for analyzing platelet and megakaryocyte function. The approaches presented for platelet analysis include aggregometry, secretion, arachidonic acid metabolism, procoagulent response, platelet adhesion under static and flow conditions, flow cytometry, and production of microparticles. The techniques for study of megakaryocyte function allow the measurement of specialized structures for platelet production, the appearance of platelet-specific surface receptors, and the increase in ploidy. Volume 2 offers techniques for studying many aspects of signaling in platelets and megakaryocytes, as well as state-of-the-art commentaries on our understanding of these cells. The methods include ligand-binding assays, the study of protein and lipid kinases and phosphatases, the analysis of lipid rafts, and the measurement of intracellular calcium levels. There are also techniques for study of electrophysiological events, nitric oxide signaling, venom proteins, and for the internalization of proteins into platelets through permeabilization. This volume also describes the application of molecular and post-genomic methods for the study of platelets and megakaryocytes. All protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. The two volumes offer novice and experienced cell biologists, hematologists, and clinicians not only a benchmark survey of the field, but also a comprehensive library of proven techniques essential for productive research on platelets and megakaryocytes today.


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Endocrine-Disrupting Chemicals: From Basic Research to Clinical Practice (Contemporary Endocrinology)



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  • Publisher:   Humana Press
  • Number Of Pages:   300
  • Publication Date:   2007-06
  • Sales Rank:  
  • ISBN / ASIN:   1588298302
  • EAN:   9781588298300
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians� office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs



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B Cell Protocols (Methods in Molecular Biology)



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  • Publisher:   Humana Press
  • Number Of Pages:   304
  • Publication Date:   2004-05-12
  • Sales Rank:   296168
  • ISBN / ASIN:   1588293475
  • EAN:   9781588293473
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

A diverse collection of protocols ranging from the latest inventions and applications to some classic, but still frequently used, methods for studying B-lymphocyte development and function in higher animals. These readily reproducible protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.


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Cell Migration: Developmental Methods and Protocols (Methods in Molecular Biology)



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  • Publisher:   Humana Press
  • Number Of Pages:   364
  • Publication Date:   2004-11-30
  • Sales Rank:   1464171
  • ISBN / ASIN:   1588293823
  • EAN:   9781588293824
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

A collection of classic, novel, and state-of-the-art methods for the study of cell migration in cultured cells, different model organisms, and specialized cells in normal development and disease. Highlights include basic assays that apply to all cell migration studies in vitro, assays in various model organisms, and assays for cancer cells, endothelial cells, and neurons both in vitro and in animal models. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

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Cancer Chemoprevention: Volume 1: Promising Cancer Chemopreventive Agents (Cancer Drug Discovery and Development)



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  • Publisher:   Humana Press
  • Number Of Pages:   680
  • Publication Date:   2004-06-04
  • Sales Rank:   2869611
  • ISBN / ASIN:   158829076X
  • EAN:   9781588290762
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

A comprehensive reference survey on the identification and development of promising cancer chemopreventive agents that will help stimulate further novel research and new approvable drugs. For each agent, the authors review the relevant mechanisms of action, the criteria for populations benefiting from intervention, the safety and pharmacodynamics, clinical study design emphasizing the use of precancers, and early associated cellular and molecular biomarkers of carcinogenesis. The pharmacologic and/or mechanistic classes discussed range from antimutagens, antiinflammatories, and the nuclear receptor superfamily, to signal transduction modulators, antioxidants, vitamins, and minerals. The overall focus is on molecular targets and mechanisms. A second volume, Strategies in Chemoprevention, describes the exciting methodologies that will accelerate progress in this field and discusses the state of clinical development of chemoprevention in the various human cancer target organs.

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Cancer Chemoprevention: Volume 2: Strategies for Cancer Chemoprevention (Cancer Drug Discovery and Development)



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  • Publisher:   Humana Press
  • Number Of Pages:   568
  • Publication Date:   2005-02-01
  • Sales Rank:   2190849
  • ISBN / ASIN:   1588290778
  • EAN:   9781588290779
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

Leading researchers comprehensively describe the exciting methodologies that are accelerating progress in chemoprevention and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design. The emphasis is on documenting the characterization and application of reliable biomarkers during chemopreventive drug development. Highlights include an elegant approach to identifying chemopreventive agents in natural products, the development of preclinical models for evaluating potential chemopreventive agents, the genomics and proteomics of potential applications, and approaches for determining which populations will likely benefit from chemopreventive intervention. A companion volume, Promising Cancer Chemopreventive Agents, comprehensively surveys those agents that have promise, or have already been successfully used, to treat precancerous conditions or inhibit carcinogenesis.


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Bone Regeneration and Repair: Biology and Clinical Applications



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  • Publisher:   Humana Press
  • Number Of Pages:   416
  • Publication Date:   2005-02-17
  • Sales Rank:   497883
  • ISBN / ASIN:   0896038475
  • EAN:   9780896038479
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.



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Computational Genetics and Genomics: Tools for Understanding Disease



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  • Publisher:   Humana Press
  • Number Of Pages:   320
  • Publication Date:   2005-04-25
  • Sales Rank:   1172680
  • ISBN / ASIN:   1588291871
  • EAN:   9781588291875
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
  • Total Reviews:  



Book Description:

Well-recognized computational geneticists review and assess both currently available and developing tools for the rapid identification of the genetic basis for susceptibility to disease. The authors introduce a new computational approach that makes it possible to identify the genetic basis for differences in physiologic or pathologic responses among inbred mouse strains, thus facilitating more rapid genetic discovery. The focus is on the haplotype-based computational genetic analysis method and its application to inbred mouse strains. Reviewing murine models of asthma, lung disease, osteoporosis, and substance abuse, the contributors provide an overview of available mouse models, what has been learned from them, and which new models must be developed to advance our understanding of these diseases. They also describe how genetic analysis of human populations has yielded information on the genetic basis for susceptibility to asthma and other inflammatory diseases.


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Autoimmunity: Methods and Protocols (Methods in Molecular Medicine)



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  • Publisher:   Humana Press
  • Number Of Pages:   448
  • Publication Date:   2004-08-01
  • Sales Rank:   2150444
  • ISBN / ASIN:   1588292312
  • EAN:   9781588292315
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

This collection of readily reproducible molecular techniques and related in vitro/in vivo model systems can be used to explore the causes of autoimmunity, as well as how best it may be regulated. There are methods to assess immunological and biochemical pathways relevant for pathogenesis and to establish and assess a variety of autoimmune diseases, including arthritis, lupus, diabetes, multiple sclerosis, myocarditis, thyroiditis, scleroderma, uveitis, and vitiligo.



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Antisense Therapeutics (Methods in Molecular Medicine)



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  • Publisher:   Humana Press
  • Number Of Pages:   344
  • Publication Date:   2004-09-16
  • Sales Rank:   3219483
  • ISBN / ASIN:   1588292053
  • EAN:   9781588292056
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
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Book Description:

A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs.



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Cardiovascular Genomics (Contemporary Cardiology)



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  • Publisher:   Humana Press
  • Number Of Pages:   376
  • Publication Date:   2005-01-06
  • Sales Rank:   3654368
  • ISBN / ASIN:   1588294005
  • EAN:   9781588294005
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
  • Total Reviews:  



Book Description:

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

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Cartilage and Osteoarthritis (Methods in Molecular Medicine)



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  • Publisher:   Humana Press
  • Number Of Pages:   376
  • Publication Date:   2004-07-28
  • Sales Rank:   1649374
  • ISBN / ASIN:   1588292479
  • EAN:   9781588292476
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
  • Total Reviews:  



Book Description:

An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for studies-at the tissue level-of turnover, structure, and functioning of normal and diseased cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists with readily reproducible protocols for new experiments to understand-from the cellular to the animal level-the pathophysiology of cartilage and to discover molecular targets for pharmacological intervention.

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Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)



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  • Publisher:   Humana Press
  • Number Of Pages:   292
  • Publication Date:   2004-12-03
  • Sales Rank:   2336194
  • ISBN / ASIN:   1588292002
  • EAN:   9781588292001
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
  • Total Reviews:  



Book Description:

Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.

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Amyloid Proteins (Methods in Molecular Biology)



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  • Publisher:   Humana Press
  • Number Of Pages:   408
  • Publication Date:   2004-12-28
  • Sales Rank:   1629342
  • ISBN / ASIN:   1588293378
  • EAN:   9781588293374
  • Binding:   Hardcover
  • Manufacturer:   Humana Press
  • Studio:   Humana Press
  • Average Rating:  
  • Total Reviews:  



Book Description:

A proven collection of readily reproducible techniques for studying amyloid proteins and their involvement in the etiology, pathogenesis, diagnosis, and therapy of amyloid diseases. The contributors provide methods for the preparation of amyloid and its precursors (oligomers and protofibrils), in vitro assays and analytical techniques for their study, and cell culture models and assays for the production of amyloid proteins. Additional chapters present readily reproducible techniques for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.


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Ecografia Vaginal



By Carlos E. Bonilla

  • Publisher:   Editorial Medica Panamericana
  • Number Of Pages:  
  • Publication Date:   2001-10
  • Sales Rank:  
  • ISBN / ASIN:   8479035668
  • EAN:   9788479035662
  • Binding:   Paperback
  • Manufacturer:   Editorial Medica Panamericana
  • Studio:   Editorial Medica Panamericana
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Rhinologic and Sleep Apnea Surgical Techniques



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  • Publisher:   Springer
  • Number Of Pages:   458
  • Publication Date:   2007-06
  • Sales Rank:   1148508
  • ISBN / ASIN:   354034019X
  • EAN:   9783540340195
  • Binding:   Hardcover
  • Manufacturer:   Springer
  • Studio:   Springer
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Book Description:

As technology advances, practicing or training otolaryngologists register in educational courses to refresh their surgical skills and stay abreast of these changes. While information is becoming available in several journals, there is a definite need for a single surgical atlas-like book that contains precise descriptions of the surgical techniques used in rhinology and sleep apnea surgery. Each chapter was written by surgeons with extensive experience in each topic who have already published on the specific procedure described. Each chapter contains diagrammatic or illustrative descriptions of surgical techniques and provides tips and pearls of wisdom to avoid complications when the procedures are performed. This comprehensive work of surgical information serves as a valuable resource for otolaryngologists in training to augment their surgical education and for practicing otolaryngologists as a review source to best approach the surgical pathologies they encounter in their practice of rhinology and treatment of sleep apnea.

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